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August 19, 2025LifeOpen Access

Encephalitis: Predictive Role of Clinical and Diagnostic Data on Outcome—A Monocentric Study

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Authors

DEDeborah K. ErhartLBLuisa T. BalzHTHayrettin Tumani

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Overview

Retrospective analysis shows clinical predictors of functional outcome in encephalitis patients, indicating their prognostic importance.

Key Points

  • Key predictors of poor functional outcome included altered consciousness and specific EEG patterns, signifying their role in prognosis.
  • Three multivariate models explained up to 53% of variance in functional outcomes as measured by the modified Rankin Scale (mRS).
  • The study employed ordinal logistic regression to assess clinical, demographic, and diagnostic factors impacting outcomes in 98 patients diagnosed with infectious encephalitis.
  • Findings emphasize the importance of initial neurological status and neuroimaging in assessing infectious encephalitis, despite the study's limitations.

Cite This Study

Erhart et al. (2025) studied this question.

synapsesocial.com/papers/68af33ddcf1dd9ea359e8cbchttps://doi.org/10.3390/life15081313
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical and Laboratory Predictors of Poor Neurological Outcomes Following Infectious Encephalitis: Systematic Review and Meta‐Analysis2025
  2. 2Outcomes of Critically Ill Adult Patients With Acute Encephalitis2025
  3. 3Clinical Features and Outcomes in Adult Patients with Autoimmune Encephalitis Requiring Intensive Care: A Retrospective Cohort Study2025 · 2 citations
  4. 4Multivariate Risk-Factor Analysis of Short-Term Poor Prognosis in Children With Autoimmune Encephalitis2026
  5. 5Clinical characteristics and outcomes of anti-NMDA receptor-dominant autoimmune encephalitis2026