Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 16, 2025DiabetologiaOpen Access

The utility of early gestational OGTT and biomarkers for the development of gestational diabetes mellitus: an international prospective multicentre cohort study

View Full Paper
Ask AI
Bookmark
Share

Authors

EHEvelyn A. HuhnGKGrammata KotzaeridiTFThorsten Fischer

Discussion

Loading...

Member takes

Overview

Prospective multicentre cohort study finds early OGTT and biomarkers predict gestational diabetes risk, suggesting new protocols.

Key Points

  • Early gestational OGTT glucose concentrations were predictive of developing gestational diabetes mellitus (GDM).
  • In the cohort of 657 women, 12.6% (83 women) were found to develop GDM with OGTT results showing areas under the curve ranging from 0.68 to 0.74.
  • The prospective cohort study utilized both an early OGTT and biomarkers to assess glucose homeostasis at 13.4 weeks gestation.
  • These findings may inform protocols distinguishing low- and high-risk pregnancies for gestational diabetes.

Cite This Study

Huhn et al. (2025) studied this question.

synapsesocial.com/papers/68af2b68cf1dd9ea359e4f32https://doi.org/10.1007/s00125-025-06517-0
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pancreatic beta-cell secretory products in the diagnosis and risk stratification of gestational diabetes mellitus: a prospective longitudinal cohort study2025
  2. 2First‐trimester biomarkers of gestational diabetes mellitus: A scoping review2025
  3. 3Long‐term risk prediction of diabetes mellitus using the 100‐g oral glucose tolerance test during pregnancy: Insights into test patterns, single abnormal values, and abnormal fasting glucose2025
  4. 4Sonographic and Biochemical Markers in Gestational Diabetes Mellitus: A Prospective Cohort Study at a Tertiary Hospital in Greece2025
  5. 5Association Between Hypoglycaemia at the 24–28th-Week OGTT and Obstetric and Neonatal Outcomes in Women with Gestational Diabetes2025