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September 10, 2025BMJ OpenOpen Access

Pancreatic beta-cell secretory products in the diagnosis and risk stratification of gestational diabetes mellitus: a prospective longitudinal cohort study

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Authors

GDGareth DunseathMAMichael AtkinsonWCWY Cheung

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Overview

Prospective cohort study evaluates pancreatic beta-cell products' role in diagnosing gestational diabetes, suggesting C-peptide as a key indicator.

Key Points

  • C-peptide levels significantly differed between groups, indicating its potential role in GDM diagnosis.
  • The study analyzed hormonal concentrations from 66 pregnant women, despite COVID-19 recruitment challenges.
  • Comparison of hormone levels revealed no significant difference in proinsulin and insulin across groups.
  • Results suggest further research is necessary to confirm findings in a larger cohort.

Cite This Study

Dunseath et al. (2025) studied this question.

synapsesocial.com/papers/68c23caeb210217d6478ab55https://doi.org/10.1136/bmjopen-2025-100039
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