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August 16, 2025PatientOpen Access

A Qualitative Study on Patient Experience with Signs, Symptoms, and Daily Impacts of Immune Thrombocytopenia

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Authors

WGWaleed GhanimaNCNichola CooperSBSylvie Bozzi

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Overview

Qualitative study reveals key ITP symptoms and impacts on health-related quality of life, highlighting significant patient concerns.

Key Points

  • Fatigue was reported by 94% of patients, marking it as the most prominent symptom of immune thrombocytopenia.
  • Six key impacts were identified, with 72% of patients noting work-related challenges stemming from ITP.
  • Concept elicitation interviews provided insights into symptom experiences and quality of life in patients with ITP.
  • The study updated the conceptual model of health-related quality of life based on patient feedback, ensuring relevancy in assessments.

Cite This Study

Ghanima et al. (2025) studied this question.

synapsesocial.com/papers/68af2b68cf1dd9ea359e4e64https://doi.org/10.1007/s40271-025-00762-6
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Exploring the Burden on Patients Living With and Receiving Treatment for Immune Thrombocytopenia ( <scp>ITP</scp> ): Patient and Physician Perceptions From the <scp>ITP</scp> World Impact Survey (I‐ <scp>WISh</scp> ) 2.02026
  2. 2Patient survey in immune thrombocytopenia (<scp>ITP</scp>): Identifying unmet needs related to treatment and disease control in patients living in the United States2025
  3. 3Plasma Interleukin-12 Levels as a Potential Biomarker of Fatigue and Quality of Life in Primary Immune Thrombocytopenia2025
  4. 4Clinician’s knowledge and awareness of patient-reported outcomes in immune thrombocytopenia: Results of a national survey (ITP NET, GIMEMA Working Group Anemia and Thrombocytopenia)2025
  5. 5Association of Cognitive Impairment with Reduced Health-Related Quality of Life and Depression Among Survivors of Thrombotic Thrombocytopenic Purpura2025