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August 17, 2025South Asian Research Journal of Applied Medical SciencesOpen Access

Impact of UTI in Both T2DM with and without Nephropathy on Renal Function Tests and Novel Biomarkers (Liver Fatty Acid Binding Protein (LFABP) and Secretory Leukocyte Protease Inhibitor (SLPI))

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Authors

HSH. ShakerSMS. Mohammed

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Overview

Case-control study shows UTI affects renal function and novel biomarkers in type 2 diabetes, indicating its clinical significance.

Key Points

  • UTI significantly alters albumin levels in urine among T2DM and DN patients, showing variable effects on biomarkers.
  • Serum levels of LFABP were notably higher in type 2 diabetes with UTI compared to diabetic nephropathy cases.
  • Participants were 80 individuals, split between those with and without diabetic nephropathy, using ELISA for biomarker measurement.
  • Findings indicate that bacterial isolates influence serum urea levels, pointing to the complexity of UTI management in diabetes.

Cite This Study

Shaker et al. (2025) studied this question.

synapsesocial.com/papers/68a35316234c60ad5c20d935https://doi.org/10.36346/sarjams.2025.v07i04.013
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