Early markers of kidney damage in children with type 1 diabetes mellitus

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Study shows higher NGAL and L-FABP levels indicate kidney damage in children with type 1 diabetes, suggesting early diagnosis methods.

NGAL levels were over 3 times higher in children with type 1 diabetes experiencing kidney damage compared to healthy controls.
Children with type 1 diabetes demonstrated significant increases in urinary NGAL and L-FABP irrespective of kidney damage status.
Enzyme immunoassay measured NGAL and L-FABP concentrations in urine, linking to risk assessments for chronic kidney failure.
Elevated urinary markers can help predict the onset of chronic kidney disease in children with diabetes, highlighting the need for monitoring.

Т. П. Макарова (2025) studied this question.

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View Full Paper

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Authors

Study shows higher NGAL and L-FABP levels indicate kidney damage in children with type 1 diabetes, suggesting early diagnosis methods.

NGAL levels were over 3 times higher in children with type 1 diabetes experiencing kidney damage compared to healthy controls.
Children with type 1 diabetes demonstrated significant increases in urinary NGAL and L-FABP irrespective of kidney damage status.
Enzyme immunoassay measured NGAL and L-FABP concentrations in urine, linking to risk assessments for chronic kidney failure.
Elevated urinary markers can help predict the onset of chronic kidney disease in children with diabetes, highlighting the need for monitoring.

Т. П. Макарова (2025) studied this question.

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