August 15, 2025BMJOpen Access

7-014 Is it safe to defer revascularisation in asymptomatic patients with chronic coronary syndrome with FFR-CTpositive stenoses?

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Authors

RCRavi Chotalia ZNZ Nadheri TETony Y. Eng

Discussion

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Overview

Observational analysis found comparable event rates in asymptomatic CCS patients with positive FFR-CT stenoses, suggesting revascularisation may not be necessary for all patients.

Key Points

The primary outcome showed 5% of patients with FFR-CT negative had events while 23% of symptomatic patients with FFR-CT positive had events, indicating a higher risk in symptomatic cases.
A total of 801 patients were analyzed, with 555 meeting inclusion criteria and followed for a median of 43.3 months, providing robust long-term data on outcomes.
Patients categorized as asymptomatic with positive FFR-CT had outcomes similar to those with negative FFR-CT, which underscores the potential safety of conservative management.
Guideline-driven revascularisation limited to symptomatic patients appears safe, with no significant differences in secondary outcome events among groups.

Cite This Study

Chotalia et al. (2025) studied this question.

synapsesocial.com/papers/68a34f72234c60ad5c20c260 https://doi.org/10.1136/heartjnl-2025-bcs.210

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August 15, 2025BMJOpen Access

7-014 Is it safe to defer revascularisation in asymptomatic patients with chronic coronary syndrome with FFR-CTpositive stenoses?

View Full Paper

Ask AI

Bookmark

Authors

RCRavi Chotalia ZNZ Nadheri TETony Y. Eng

Discussion

Member takes

Overview

Observational analysis found comparable event rates in asymptomatic CCS patients with positive FFR-CT stenoses, suggesting revascularisation may not be necessary for all patients.

Key Points

The primary outcome showed 5% of patients with FFR-CT negative had events while 23% of symptomatic patients with FFR-CT positive had events, indicating a higher risk in symptomatic cases.
A total of 801 patients were analyzed, with 555 meeting inclusion criteria and followed for a median of 43.3 months, providing robust long-term data on outcomes.
Patients categorized as asymptomatic with positive FFR-CT had outcomes similar to those with negative FFR-CT, which underscores the potential safety of conservative management.
Guideline-driven revascularisation limited to symptomatic patients appears safe, with no significant differences in secondary outcome events among groups.

Cite This Study

Chotalia et al. (2025) studied this question.

synapsesocial.com/papers/68a34f72234c60ad5c20c260 https://doi.org/10.1136/heartjnl-2025-bcs.210

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