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September 5, 2025European Heart Journal - Imaging Methods and PracticeOpen Access

Comparison of Computed Tomogram Coronary Angiography (CTCA) alone versus CTCA with selective FFRCT in patients presenting with stable chest pain: a FORECAST trial substudy

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Authors

MKMohamed KiraLGLavinia GabaraMAMohamed Abouelasaad

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Overview

Prespecified analysis reveals that CTCA plus selective FFRCT is cost neutral, suggesting fewer additional tests are required for patients.

Key Points

  • The CTCA plus selective FFRCT strategy was cost neutral compared to CTCA alone at 9 months.
  • In the experimental group, 43 patients (8.9%) required additional non-invasive tests compared to 72 (16%) in the standard care group.
  • Patients in the experimental arm had a significantly reduced time to final management plan—64 days compared to 75 days in the standard care arm.
  • Patients not in the CTCA stratum had significantly higher median total cardiac costs of £908 compared to the other groups at £594.

Cite This Study

Kira et al. (2025) studied this question.

synapsesocial.com/papers/68c23a74b210217d64780923https://doi.org/10.1093/ehjimp/qyaf113
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparative Analysis of Cardiac CT and Invasive Coronary Angiography for Suspected Stable Coronary Artery Disease and Subsequent Functional Testing and Revascularization: A Prespecified Secondary DISCHARGE Randomized Trial Analysis2025
  2. 27-014 Is it safe to defer revascularisation in asymptomatic patients with chronic coronary syndrome with FFR-CT positive stenoses?2025
  3. 3Targeted Use of Computed Tomographic Coronary Angiography in Acute Chest Pain2026
  4. 4Clinical Outcomes of Computed Tomography Coronary Angiography (CTCA) in Patients With Suspected Coronary Artery Disease: A Single‐Center Experience2025
  5. 5Clinical Impact of CT-Based FFR in Everyday Cardiology: Bridging Computation and Decision-Making2025 · 10 citations