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August 15, 2025Open Access

Reliability and cross-group equivalence of the 8-item version of the Patient Health Questionnaire (PHQ-8) to screen for depression in adults with and without chronic pain: a nationally representative U.S. population study

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Authors

JRJennifer S. De La RosaGCGregory T. ChismKHKatherine E. Herder

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Overview

Cross-sectional analysis revealed comparable depression screening in adults with chronic pain, suggesting PHQ-8's effectiveness.

Key Points

  • PHQ-8 measures depressive symptoms equivalently for adults with and without chronic pain, supporting its use.
  • Clinically significant depressive symptoms were observed in 3.5% of those without chronic pain and 20.1% with chronic pain.
  • This observational survey analyzed data from 30,983 respondents in the 2019 National Health Interview Survey.
  • Findings highlight that disparities in depression prevalence among chronic pain patients are reflective of true differences.

Cite This Study

Rosa et al. (2025) studied this question.

synapsesocial.com/papers/68a34f6b234c60ad5c20c164https://doi.org/10.1101/2025.08.08.25333327
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Predictive accuracy of the 2- and 8-item versions of the PHQ in measuring symptoms of depression: Brazilian National Health Survey (PNS) 2013-20192025
  2. 2Why are we still using the PHQ-9? A Historical Review and Psychometric Evaluation of Measurement Invariance2025
  3. 3Development and psychometric evaluation of the Polish version of the Chronic Pain Acceptance Questionnaire (CPAQ)2025
  4. 4Experienced, bothered by, or both: People differ in how they understand the Patient Health Questionnaire (PHQ) items2025
  5. 5Differential Item Functioning of the Patient Health Questionnaire-9 in Decompensated Cirrhosis2025