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August 1, 2025Open Access

The Underlying Mechanisms and Emerging Strategies to Overcome Resistance in Breast Cancer

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Authors

KKKrishnaswamy KannanASAlagarsamy SrinivasanAKAarthi Kannan

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Overview

This review examines resistance mechanisms in breast cancer and highlights strategies, including AI, to improve treatment outcomes.

Key Points

  • Breast cancer remains a leading cause of cancer-related mortality among women globally.
  • Resistance mechanisms include drug transporter upregulation and genetic mutations like ESR1 and PIK3CA.
  • The study reviews metabolic and epigenetic factors contributing to treatment resistance in breast cancer.
  • Emerging strategies, including AI, offer new opportunities to enhance detection and treatment of resistant breast cancer.

Cite This Study

Kannan et al. (2025) studied this question.

synapsesocial.com/papers/689a0c65e6551bb0af8cfb5chttps://doi.org/10.20944/preprints202507.2452.v1
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Also Consider

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  1. 1The Underlying Mechanisms and Emerging Strategies to Overcome Resistance in Breast Cancer2025 · 20 citations
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  5. 5Molecular Mechanisms of Radiation Resistance in Breast Cancer: A Systematic Review of Radiosensitization Strategies2025 · 10 citations