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July 25, 2025Current Issues in Molecular BiologyOpen Access

Molecular Mechanisms of Radiation Resistance in Breast Cancer: A Systematic Review of Radiosensitization Strategies

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Authors

EMEmma MageauRDRobert Michael DerbowkaNDN Dickinson

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Overview

Systematic review identifies radiation resistance mechanisms in breast cancer, suggesting targets for radiosensitization strategies.

Key Points

  • Breast cancer is often resistant to radiation therapy, impacting treatment effectiveness.
  • Key mechanisms affecting radiation resistance include DNA damage repair and dysregulated signaling pathways.
  • Non-coding RNAs and tumor microenvironment factors also play roles in modulating radiation response.
  • Identifying these mechanisms offers new strategies for improving radiosensitivity and treatment outcomes.

Cite This Study

Mageau et al. (2025) studied this question.

synapsesocial.com/papers/689a0627e6551bb0af8ce096https://doi.org/10.3390/cimb47080589
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