Theranostics targeting fibroblast activation protein in the pan‐cancer field

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Discussion

Review highlights FAP’s role in diagnostics and therapy for solid tumors, indicating its translational potential.

FAP is a promising target for cancer diagnostics and therapy due to its overexpression in cancer-associated fibroblasts.
FAP-targeted PET/CT offers better sensitivity and specificity than conventional FDG PET/CT for detecting tumors.
TRT shows promising clinical efficacy in solid tumors, enhancing therapeutic options for patients.
The review proposes an integrated framework for implementing FAP-based theranostics in clinical settings.

Li et al. (2025) studied this question.

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