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July 19, 2025Nutrition & MetabolismOpen Access

Omega-3 supplementation and cardiometabolic risk factors in obese/overweight children and adolescents: a GRADE assessed systematic review and meta-analysis

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Authors

VMVali MusazadehMMMahsa MahmoudinezhadPPPedram Pam

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Overview

Meta-analysis reveals omega-3 PUFA supplementation reduces BMI and triglycerides in obese/overweight children, suggesting potential benefits for cardiometabolic health.

Key Points

  • Omega-3 PUFA supplementation significantly reduced BMI by 0.39 kg/m² in overweight youth.
  • Triglyceride levels decreased by 23.54 mg/dl with omega-3 supplementation in this meta-analysis.
  • A total of nine studies involving 595 participants were included in the analysis of omega-3 effects.
  • The GRADE assessment indicated high quality of evidence for improvements in BMI, HOMA-IR, and triglycerides.

Cite This Study

Musazadeh et al. (2025) studied this question.

synapsesocial.com/papers/689a02c9e6551bb0af8ccefdhttps://doi.org/10.1186/s12986-025-00952-x
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Also Consider

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  5. 5Mendelian Randomization Indicates Enhanced Lipid Control is Essential for Omega-3's Cardiovascular Protection2025