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September 20, 2025NutrientsOpen Access

Omega-3 Polyunsaturated Fatty Acids and Cognitive Decline in Adults with Non-Dementia or Mild Cognitive Impairment: An Overview of Systematic Reviews

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Authors

MBMárcia de Aguiar Ferreira BarrosTBTeresa R.S. BrandãoSISusana Couto Irving

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Overview

Systematic reviews highlight modest cognitive improvements from omega-3 fatty acids in aging populations, suggesting implications for preventive strategies.

Key Points

  • Cognition improved modestly in adults with mild cognitive impairment receiving omega-3 supplementation.
  • Meta-analysis of nine systematic reviews demonstrated a statistically significant effect size of 0.16 in MMSE scores.
  • Quality assessment with AMSTAR-2 and statistical analyses using SPSS supported a need for enhanced research.
  • Further studies are required to effectively confirm omega-3 supplementation’s role in cognitive health.

Cite This Study

Barros et al. (2025) studied this question.

synapsesocial.com/papers/68d43906713b0b5dfea789d2https://doi.org/10.3390/nu17183002
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