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July 19, 2025

Neuroprotective Potential of Curcumin in Neurodegenerative Diseases: Clinical Insights Into Cellular and Molecular Signaling Pathways.

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Authors

MIMd. Rezaul IslamARAbdur RaufSAS Akter

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Overview

Review demonstrates curcumin's neuroprotective roles in neurodegenerative diseases, highlighting oxidative stress and inflammatory pathways.

Key Points

  • Curcumin exhibits neuroprotective potential in neurodegenerative diseases like Alzheimer's and Parkinson's.
  • The compound effectively reduces oxidative stress and inflammation through NF-κB and Nrf2 pathways.
  • Research shows curcumin can cross the blood-brain barrier, enhancing neuronal survival.
  • Future studies aim to improve curcumin formulations for better bioavailability and efficacy.

Cite This Study

Islam et al. (2025) studied this question.

synapsesocial.com/papers/689a02c9e6551bb0af8cced2https://doi.org/10.1002/jbt.70369
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Neuroprotective Role of Curcumin: From Molecular Pathways to Clinical Translation—A Narrative Review2025
  2. 2Investigating The Neuroprotective Role of Curcumin in Alzheimer's Disease Models2025 · 2 citations
  3. 3Curcumin and neuroplasticity: epigenetic mechanisms underlying cognitive enhancement in aging and neurodegenerative disorders2025
  4. 4Anti-inflammatory effect of curcumin on neurological disorders: a narrative review2025
  5. 5Curcumin and Dementia: A Systematic Review of Its Effects on Oxidative Stress and Cognitive Outcomes in Animal Models2025