Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 22, 2025International Journal of Molecular SciencesOpen Access

Curcumin and Dementia: A Systematic Review of Its Effects on Oxidative Stress and Cognitive Outcomes in Animal Models

View Full Paper
Ask AI
Bookmark
Share

Authors

SKSamuel Abiodun KehindeWLWai Phyo LinBLBo Bo Lay

Discussion

Loading...

Member takes

Overview

Systematic review shows curcumin reduces oxidative stress and improves cognitive outcomes in dementia models, indicating its potential as a neuroprotective agent.

Key Points

  • Curcumin demonstrated significant reductions in malondialdehyde, indicating decreased oxidative stress in dementia models.
  • Over 80% of studies reported improved cognitive outcomes, particularly in spatial learning and memory due to curcumin's effects.
  • A review of 29 preclinical studies utilized various rodent models of dementia to assess curcumin's neuroprotective effects.
  • Findings suggest curcumin's antioxidative and anti-inflammatory properties may offer new therapeutic avenues for neurodegenerative diseases.

Cite This Study

Kehinde et al. (2025) studied this question.

synapsesocial.com/papers/689a0614e6551bb0af8cd62ehttps://doi.org/10.3390/ijms26147026
View Full Paper
Ask AI
Bookmark
Share