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July 26, 2026PeerJOpen Access

Not all migrants are the same: geographic origin and long-term outcomes after first-episode psychosis—a retrospective cohort study

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Authors

ATAlba TollSSSara SillesYMYolanda Manzano

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Overview

Retrospective cohort study investigates psychiatric outcomes in migrant populations after first-episode psychosis, suggesting tailored treatment approaches.

Key Points

  • This study aims to explore how geographic origin and migration timing affect psychiatric outcomes following first-episode psychosis in migrants.
  • Retrospective cohort study conducted over 5 years on 184 patients attending Early Intervention Service
  • Patients grouped by geographic origin (e.g., Spanish, Latin American, Maghrebi, Sub-Saharan) and migration recency
  • Logistic regression and survival analyses to evaluate treatment adherence, relapse, and service disengagement.
  • Maghrebi origin linked to lower treatment adherence (OR = 0.32, 95% CI [0.12–0.89], p = 0.030)
  • Higher hazard of service disengagement for Maghrebi patients (HR = 2.42, 95% CI [1.10–5.34], p = 0.028)
  • Recent migrants (≤5 years) have increased disengagement hazard (HR = 2.89, 95% CI [1.30–6.40], p = 0.009), and Sub-Saharan origin is associated with earlier LAI antipsychotic initiation (HR = 3.40, 95% CI [1.58–7.32], p = 0.002).

Cite This Study

Toll et al. (2026) studied this question.

synapsesocial.com/papers/6a65a6f2d3aea3239cd78071https://doi.org/10.7717/peerj.21391
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The impact of socioeconomic factors on the incidence and characteristics of first-episode psychosis2025 · 1 citations
  2. 2Risk Factors for Psychosis in the Migrant Population in Morocco2025
  3. 3Sex differences in outcomes of first episode psychosis: results from an early intervention service2025 · 4 citations
  4. 4Long-Term Outcomes in First-Episode Psychosis: Insights from a 20-Year Cohort Study to Inform Recovery-Oriented Care Models2025
  5. 5Long-term diagnostic stability, predictors of diagnostic change, and time until diagnostic change of first-episode psychosis: a 21-year follow-up study2025