What is the clinical evidence from this study?

Study design: Cohort. Population: Coronary artery disease post-PCI (n=3417). Intervention: Diabetes mellitus vs. Without diabetes mellitus. Primary outcome: Changes in quality of life (RAND-12 and MIDAS scores).

What question did this study set out to answer?

This research aims to evaluate the differences in quality of life for patients with and without diabetes mellitus after percutaneous coronary intervention.

July 18, 2026European Journal of Cardiovascular Nursing

Diabetes linked to smaller improvements in physical quality of life 12 months post-PCI.

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Why the study?

Does the presence of diabetes mellitus affect quality of life trajectories over 12 months in patients after percutaneous coronary intervention?

Population

3,417 patients after percutaneous coronary intervention, mean age 66 years, 78% men. 621 patients had…

Comparison

Presence of diabetes mellitus vs Absence of diabetes mellitus

Design

Cohort

Follow-up

12 months

Key result

Following PCI, patients with diabetes mellitus had significantly smaller improvements in physical quality of life at 12 months compared to those without diabetes.

Authors

AKA Kjoelseth TNT N Tone Norekvaal MHM C Hagen

Discussion

Member takes

Overview

DM associated with smaller post-PCI QoL gains; hypothesis-generating for comorbidity-specific strategies, prospective trials needed.

Key Points

This research aims to evaluate the differences in quality of life for patients with and without diabetes mellitus after percutaneous coronary intervention.
Prospective multicentre cohort study with 3417 patients (621 with DM) after PCI.
Quality of life was assessed using RAND-12 and MIDAS at multiple timepoints (2, 6, and 12 months).
Statistical analysis included generalised linear models with adjustments for sociodemographic factors.
Quality of life improved for all patients across timepoints, with no significant differences between groups.
Patients with diabetes experienced smaller improvements in physical component scores at 12 months compared to those without.
Significant positive changes in MIDAS concerns domain were greater for patients with diabetes at 6 and 12 months.

Study Design

Type

Cohort (n=3,417)

Multicenter

Yes

Structured PICO

Does the presence of diabetes mellitus affect quality of life trajectories over 12 months in patients after percutaneous coronary intervention?

Population

3,417 patients treated with percutaneous coronary intervention, including 621 with diabetes mellitus, followed for 12 months to assess quality of life.

Exposure

Presence of diabetes mellitus

Comparator

Absence of diabetes mellitus

Outcome

Changes in quality of life (QoL) from index admission to 2-, 6- and 12 months after hospital discharge, assessed using the RAND-12 Item Short Form Health Survey (RAND-12) and the Myocardial Infarction Dimensional Assessment Scale (MIDAS)patient reported

Patients with and without diabetes mellitus experience similar overall improvements in quality of life up to 12 months after PCI, though physical improvements may be slightly attenuated in those with diabetes.

Cite This Study

Kjoelseth et al. (2026) conducted a cohort in Coronary artery disease post-PCI (n=3,417). Diabetes mellitus vs. Without diabetes mellitus was evaluated on Changes in quality of life (RAND-12 and MIDAS scores). Following PCI, patients with diabetes mellitus had significantly smaller improvements in physical quality of life at 12 months compared to those without diabetes.

synapsesocial.com/papers/6a5b38f68167787360d24e47 https://doi.org/10.1093/eurjcn/zvag155.058

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July 18, 2026European Journal of Cardiovascular Nursing

Diabetes linked to smaller improvements in physical quality of life 12 months post-PCI.

View Full Paper

Ask AI

Bookmark

Why the study?

Does the presence of diabetes mellitus affect quality of life trajectories over 12 months in patients after percutaneous coronary intervention?

Population

3,417 patients after percutaneous coronary intervention, mean age 66 years, 78% men. 621 patients had…

Comparison

Presence of diabetes mellitus vs Absence of diabetes mellitus

Design

Cohort

Follow-up

12 months

Key result

Following PCI, patients with diabetes mellitus had significantly smaller improvements in physical quality of life at 12 months compared to those without diabetes.

Authors

AKA Kjoelseth TNT N Tone Norekvaal MHM C Hagen

Discussion

Member takes

Overview

DM associated with smaller post-PCI QoL gains; hypothesis-generating for comorbidity-specific strategies, prospective trials needed.

Key Points

This research aims to evaluate the differences in quality of life for patients with and without diabetes mellitus after percutaneous coronary intervention.
Prospective multicentre cohort study with 3417 patients (621 with DM) after PCI.
Quality of life was assessed using RAND-12 and MIDAS at multiple timepoints (2, 6, and 12 months).
Statistical analysis included generalised linear models with adjustments for sociodemographic factors.
Quality of life improved for all patients across timepoints, with no significant differences between groups.
Patients with diabetes experienced smaller improvements in physical component scores at 12 months compared to those without.
Significant positive changes in MIDAS concerns domain were greater for patients with diabetes at 6 and 12 months.

Study Design

Type

Cohort (n=3,417)

Multicenter

Yes

Structured PICO

Does the presence of diabetes mellitus affect quality of life trajectories over 12 months in patients after percutaneous coronary intervention?

Population

3,417 patients treated with percutaneous coronary intervention, including 621 with diabetes mellitus, followed for 12 months to assess quality of life.

Exposure

Presence of diabetes mellitus

Comparator

Absence of diabetes mellitus

Outcome

Cite This Study

synapsesocial.com/papers/6a5b38f68167787360d24e47 https://doi.org/10.1093/eurjcn/zvag155.058

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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