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July 26, 2026The Journal of Cardiovascular Nursing

Family history, unhealthy lifestyle, and depressive symptoms linked to lower HRQoL in CHD and T2DM.

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Why the study?

What factors influence health-related quality of life in patients with coronary heart disease and type 2 diabetes mellitus?

Population

207 patients with coronary heart disease and type 2 diabetes mellitus from a tertiary hospital in Shiyan

Design

Cross-sectional

Key result

Among patients with CHD and T2DM, the mean EQ-5D-5L score was 0.96, with family history, unhealthy lifestyle, and depressive symptoms significantly associated with lower health-related quality of life.

Authors

XLXin LiuLBLele BiQJQiaoyun Jin

Discussion

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Overview

Depressive symptoms and unhealthy lifestyle associate with lower HRQoL in CHD-T2DM; leaves open whether interventions improve outcomes in prospective studies.

Key Points

  • Evaluate health-related quality of life in patients with coronary heart disease and type 2 diabetes, and identify factors influencing it.
  • Cross-sectional study among 207 patients with coronary heart disease and type 2 diabetes
  • Used questionnaires to assess health-related quality of life, medication adherence, and depression
  • Data analyzed using single-factor analysis and multiple linear regression
  • Mean Euro Quality-of-Life score was 0.96 (SD=0.09), with pain/discomfort and anxiety/depression common
  • Family history, knowledge of the Chinese Food Guide Pagoda, sleep duration, work schedule regularity, and depression were associated with HRQoL
  • Healthy lifestyle behavior and depressive symptoms linked to lower HRQoL

Study Design

Type

Cross-Sectional (n=207)

Multicenter

No

Structured PICO

What factors influence health-related quality of life in patients with coronary heart disease and type 2 diabetes mellitus?

P
Population
207 patients with coronary heart disease and type 2 diabetes mellitus from a tertiary hospital in Shiyan.
O
Outcome
Health-related quality of life (HRQoL) measured by Euro Quality-of-Life 5 Dimensions 5-Level Questionnairepatient reported

Patients with concurrent CHD and T2DM have relatively high HRQoL, but depressive symptoms and unhealthy lifestyle behaviors are significantly associated with lower HRQoL, highlighting targets for intervention.

Cite This Study

Liu et al. (2026) conducted a cross-sectional in Coronary heart disease and type 2 diabetes mellitus (n=207). Sociodemographic, lifestyle, and psychological factors was evaluated on Health-related quality of life (HRQoL) measured by Euro Quality-of-Life 5 Dimensions 5-Level Questionnaire. Among patients with CHD and T2DM, the mean EQ-5D-5L score was 0.96, with family history, unhealthy lifestyle, and depressive symptoms significantly associated with lower health-related quality of life.

synapsesocial.com/papers/6a65a468d3aea3239cd77013https://doi.org/10.1097/jcn.0000000000001323
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Also Consider

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  5. 5Quality of life and its associated factors among patients with type 2 diabetes mellitus in East Bolaang Mongondow, Indonesia: A cross-sectional study2025