Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 3, 2026Clinical Journal of the American Society of Nephrology

CKM syndrome framework integrates multidisciplinary lifestyle and targeted pharmacotherapies to reduce morbidity and mortality.

View Full Paper
Ask AI
Bookmark
Share

Design

Review

Key result

The cardiovascular-kidney-metabolic (CKM) syndrome framework emphasizes multidisciplinary care, combining lifestyle interventions with targeted pharmacotherapies to reduce morbidity and mortality.

Authors

TJTazeen H. JafarAZAnqi ZhuOOOluwabunmi Ogungbe

Discussion

Loading...

Member takes

Overview

CKM syndrome may prompt integrated clinical care in disadvantaged groups; leaves open targeted interventions for visceral obesity and disparities.

Key Points

  • This review focuses on the cardiovascular-kidney-metabolic (CKM) syndrome and its multifaceted determinants, aiming to enhance clinical action and care.
  • Synthesized current evidence on CKM syndrome development and progression.
  • Highlighted biological mechanisms, shared risk factors, and social determinants of health.
  • Outlined practical strategies to integrate CKM care into clinical practice.
  • Proposed a five-stage continuum to assess cardiovascular morbidity and mortality risk.
  • Emphasized the need for multidisciplinary approaches combining lifestyle changes and pharmacotherapies.
  • Identified emerging strategies to enhance feasibility and sustainability of CKM care integration.

PICO

P
Population
Cardiovascular-kidney-metabolic (CKM) syndrome
E
Exposure / Comparator
Multidisciplinary CKM care

The paper highlights the AHA cardiovascular-kidney-metabolic (CKM) syndrome framework and emphasizes the need for multidisciplinary care combining lifestyle interventions with targeted pharmacotherapies.

Cite This Study

Jafar et al. (2026) conducted a review in Cardiovascular-kidney-metabolic (CKM) syndrome. Multidisciplinary CKM care was evaluated. The cardiovascular-kidney-metabolic (CKM) syndrome framework emphasizes multidisciplinary care, combining lifestyle interventions with targeted pharmacotherapies to reduce morbidity and mortality.

synapsesocial.com/papers/6a4755ae5c29257aa257aa98https://doi.org/10.2215/cjn.0000001173
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ASN Kidney Health Guidance on the Cardiovascular-Kidney-Metabolic Syndrome2026
  2. 2Cardiovascular-kidney-metabolic-syndrome: a modern view of the problem2025
  3. 3From Metabolic Syndrome to Cardiovascular–Kidney–Metabolic Syndrome and Systemic Metabolic Disorder: A Call to Recognize the Progressive Multisystemic Dysfunction2025
  4. 4Contemporary and Emerging Therapeutics in Cardiovascular-Kidney-Metabolic (CKM) Syndrome: In Memory of Professor Akira Endo2025 · 1 citations
  5. 5Contemporary and Emerging Therapeutics in Cardiovascular-Kidney-Metabolic (CKM) Syndrome: In Memory of Professor Akira Endo2025