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June 20, 2026F1000ResearchOpen Access

Endocrine dysfunctions in patients with beta thalassemia major: a single-center retrospective study from Basrah

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Authors

HAHaider Ayad AlidrisiHNHussein NwayyirMAMahmood Thamer Altemimi

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Overview

Retrospective study assesses endocrine dysfunction prevalence in beta thalassemia major patients, indicating the need for regular evaluations.

Key Points

  • This study aims to assess the prevalence of various endocrine dysfunctions in patients with beta thalassemia major.
  • Retrospective study including 496 patients with beta thalassemia major.
  • Patients underwent detailed endocrine assessments for related complaints from Jan 2010 to Dec 2023.
  • Participants were referred from Basra Center for hereditary blood diseases to a specialized center.
  • Mean age for endocrine evaluation was 13.6 years with no gender differences.
  • 16.8% prevalence of endocrine dysfunctions, with common issues being growth hormone deficiency (6.0%), diabetes mellitus (4.9%), and hypogonadism (4.5%).
  • 78.7% of patients had a single endocrine dysfunction, while 16.5% had two, and 4.8% had three or more.

Cite This Study

Alidrisi et al. (2026) studied this question.

synapsesocial.com/papers/6a362fe6db0793dc1a5372behttps://doi.org/10.12688/f1000research.182800.1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prevalence of Endocrinopathies in Beta Thalassemia Major Patients attending Al-Faihaa Specialized Endocrine Center at Al-Basra City2025
  2. 2Endocrine Manifestations in Children and Adolescents with Thalassemia Major - A Prospective Cohort Study2025
  3. 3Endocrine complications in patients with β-thalassemia major receiving iron-chelation therapy2025 · 6 citations
  4. 4Endocrinopathies in adult Egyptian thalassemia patients, a cross-section study, single-center experience2025 · 1 citations
  5. 5Endocrine and metabolic manifestations of thalassemia in Bangladeshi patients: A narrative review2025