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June 20, 2026Internal MedicineOpen Access

Severe Acute Meningoencephalitis Associated with Mycoplasma pneumoniae Infection in a Young Adult Successfully Treated with Immunotherapy

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Authors

KHKotaro HarunaHYHajime YoshimuraMKMichi Kawamoto

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Overview

Case report shows rapid neurological recovery in a young adult with meningoencephalitis, suggesting early immunotherapy enhances outcomes.

Key Points

  • This case report aims to highlight the immune-mediated effects of Mycoplasma pneumoniae in meningoencephalitis.
  • Descriptive case report of a 23-year-old male diagnosed with meningoencephalitis following pneumonia.
  • Assessment included cerebrospinal fluid analysis, brain MRI, PCR, and serological testing for M. pneumoniae.
  • Interventions involved antimicrobial therapy, steroids, and intravenous immunoglobulin.
  • Neurological deterioration was noted despite initial antimicrobial therapy.
  • Rapid and complete neurological recovery occurred after the administration of steroids and intravenous immunoglobulin.
  • This case emphasizes the importance of considering immunotherapy early in similar clinical scenarios.

Cite This Study

Haruna et al. (2026) studied this question.

synapsesocial.com/papers/6a362de1db0793dc1a535d90https://doi.org/10.2169/internalmedicine.7238-26
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Case Report: severe Mycoplasma pneumoniae-associated acute disseminated encephalomyelitis in an adult: challenges in diagnosis and management2025 · 2 citations
  2. 2Acute Necrotizing Encephalopathy and Cerebral Infarction Triggered by Mycoplasma pneumoniae Infection in a Pediatric Patient: A Rare Clinical Association2025
  3. 3When Fever Strikes Twice: A Case Report of <em>Streptococcus pneumoniae</em> Myelitis with Delayed-Onset Reactive Arthritis2025
  4. 4Basal Ganglia Involvement in Pediatric Mycoplasma pneumoniae Meningoencephalitis: Two Cases and a Literature Review2025
  5. 5Escherichia coli K1 and Streptococcus pneumoniae meningitis in a young adult: a case report2025