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September 5, 2025Frontiers in MedicineOpen Access

Case Report: severe Mycoplasma pneumoniae-associated acute disseminated encephalomyelitis in an adult: challenges in diagnosis and management

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Authors

KFKatharina FeilBRBenjamin RufFBFelix Behling

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Overview

Case report reveals rapid deterioration and management challenges in M. pneumoniae-associated ADEM in an adult.

Key Points

  • The patient experienced severe neurological decline, requiring emergency decompressive hemicraniectomy.
  • Diagnostic workup indicated elevated M. pneumoniae IgM and borderline PCR positivity.
  • Successful treatment involved corticosteroids, intravenous immunoglobulin, and azithromycin.
  • This case underscores the importance of recognizing CNS manifestations related to M. pneumoniae.

Cite This Study

Feil et al. (2025) studied this question.

synapsesocial.com/papers/68c23922b210217d6477abcfhttps://doi.org/10.3389/fmed.2025.1627241
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