Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 19, 2026JACC Case ReportsOpen Access

Radical pericardiectomy with VA-ECMO support reverses severe biventricular dysfunction in a case of constrictive tuberculous pericarditis.

View Full Paper
Ask AI
Bookmark
Share

Population

A 20-year-old man with progressive heart failure, severe biventricular systolic dysfunction, and marked…

Design

Case_report

Key result

Radical pericardiectomy supported by VA-ECMO led to the complete recovery of severe biventricular systolic dysfunction in a 20-year-old man with constrictive tuberculous pericarditis.

Authors

MEMohamed ElmorshidyAHAyman HelalMEMohammed El-din

Discussion

Loading...

Member takes

Overview

Severe systolic dysfunction in pericardial disease may warrant empirical TB therapy in select cases; leaves open need for diagnostic validation and prospective data.

Key Points

  • This study aims to explore the effects of ECMO-supported pericardiectomy in patients with constrictive tuberculous pericarditis and severe ventricular dysfunction.
  • 20-year-old male with heart failure and severe biventricular dysfunction underwent radical pericardiectomy
  • Postoperative management included veno-arterial extracorporeal membrane oxygenation due to cardiogenic shock
  • Histopathology and PCR confirmed tuberculosis on pericardial tissue.
  • Severe biventricular systolic dysfunction (LVEF <15%) occurred, which improved to normal following pericardiectomy.
  • The postoperative recovery was achieved after ECMO support, indicating that the dysfunction was likely reversible due to mechanical constraints.
  • Histopathological evidence confirmed the diagnosis of tuberculosis in pericardial tissue.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
A 20-year-old man with progressive heart failure and severe biventricular systolic dysfunction due to constrictive tuberculous pericarditis.
I
Intervention
Radical pericardiectomy supported by postoperative veno-arterial extracorporeal membrane oxygenation (VA-ECMO), empirical antituberculosis therapy, and optimal heart failure treatment.
O
Outcome
Recovery of bi-ventricular systolic function

Advanced constrictive tuberculous pericarditis can manifest with profound but reversible ventricular systolic dysfunction, and timely pericardiectomy with mechanical circulatory support can be lifesaving.

Cite This Study

Elmorshidy et al. (2026) conducted a case report in Constrictive tuberculous pericarditis with severe ventricular dysfunction (n=1). Radical pericardiectomy and veno-arterial extracorporeal membrane oxygenation (VA-ECMO) was evaluated on Recovery of bi-ventricular systolic function. Radical pericardiectomy supported by VA-ECMO led to the complete recovery of severe biventricular systolic dysfunction in a 20-year-old man with constrictive tuberculous pericarditis.

synapsesocial.com/papers/6a359ab8dd3be7785e70ee2bhttps://doi.org/10.1016/j.jaccas.2026.108892
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tuberculous constrictive pericarditis: challenges and surgical management2025
  2. 2When Tuberculosis Left the Heart in a Cage: Multimodality Imaging Revealing Constrictive Pericarditis in a Young Adult2026
  3. 3A case of acute tuberculous pericarditis evolving into pericardial constriction after 32 years: A case report2025
  4. 4Identifying Constrictive Pericarditis With Multimodality Imaging2025
  5. 5Unmasking Tuberculosis: A Case of Pericardial Effusion in a Young Adult With Recurrent Pneumonia2025