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June 13, 2026Clinical Nutrition ESPENOpen Access

Pregnancy and Iron: Bridging metabolic demands and supplementation needs

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Authors

MBMichelle BedranHMHana ManceauHOHelyett Ollivier

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Overview

Randomized trial explores iron supplementation effects on maternal health and fetal outcomes, indicating vital need for targeted approaches.

Key Points

  • To examine the increased iron demands during pregnancy and the implications of iron deficiency and supplementation on maternal and fetal health.
  • Review of existing literature on maternal iron needs and supplementation strategies.
  • Analysis of the relationship between iron status and pregnancy outcomes.
  • Discussion of hepcidin regulation and its impact on iron absorption.
  • Iron deficiency during pregnancy is linked to maternal fatigue, anemia, and adverse fetal outcomes.
  • Oral iron supplementation improves iron status, but intravenous iron is effective for those who cannot tolerate oral forms.
  • Elevated maternal iron may lead to preterm birth and other complications, highlighting the need for balanced supplementation.

Cite This Study

Bedran et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf32afaef96ed7f055b0bhttps://doi.org/10.1016/j.clnesp.2026.103390
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Iron Supplementation in Pregnancy2023
  2. 2Impact of Iron Deficiency on Maternal Health During Pregnancy2025
  3. 3Associations of maternal dietary iron intake during pregnancy with infant neurodevelopment: evidence from a prospective cohort study2025
  4. 4Iron Deficiency Anemia in Pregnancy: A review2025 · 1 citations
  5. 5Iron infusions in pregnant women are associated with comparable efficacy and safety compared to non-pregnant women2025