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June 7, 2026Diabetes

Among 87 test participants, HbA1c decreased by 1.46%±1.82 (p<0.001), with high adherence participants showing greater reductions (1.7±1.5%) compared to low adherence (0.8±1.3%), while the control group showed slight glycemic worsening (+0.07%).

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Why the study?

Does a 90-day structured digital lifestyle intervention improve glycemic and anthropometric outcomes in patients with type 2 diabetes?

Population

149 participants with type 2 diabetes (n=87 in test group, n=62 in control group)

Comparison

90-day structured digital lifestyle program plus… vs Standard of care only

Design

Cohort

Follow-up

90 days

Authors

ARANNIE M. RAYMONDSKSHIVTOSH KUMARASAnkitha Sequeira

Discussion

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Overview

A 90-day structured digital lifestyle intervention with behavioral coaching significantly improves glycemic control and weight in patients with type 2 diabetes, with benefits driven largely by adherence.

Key Points

  • To assess the impact of adherence to a digital lifestyle intervention on glycemic and anthropometric outcomes in type 2 diabetes.
  • Large multicenter trial with participants assigned to intervention or control groups.
  • Test group received a structured lifestyle intervention including tailored diet, exercise, and coaching; control group followed standard care.
  • Glycemic and anthropometric measurements were taken at baseline and after 90 days.
  • Test group experienced significant reductions in HbA1c (1.46%), FBS (19.87 mg/dL), BMI (0.55 kg/m²), and weight (1.49 kg) with p<0.001 for all.
  • High adherence participants had greater reductions compared to low adherence, indicating the importance of engagement.
  • The control group showed slight worsening in HbA1c (0.07%) and FBS (10.84 mg/dL) with minimal improvement in BMI and weight.

Structured PICO

Does a 90-day structured digital lifestyle intervention improve glycemic and anthropometric outcomes in patients with type 2 diabetes?

P
Population
149 participants with type 2 diabetes (n=87 in test group, n=62 in control group)
I
Intervention
90-day structured digital lifestyle program (personalized intervention integrating circadian-aligned, tailored diet, exercise, and behavioral coaching) plus standard of care
C
Comparator
Standard of care only
O
Outcome
Glycemic and anthropometric parameters (HbA1c, fasting blood sugar, BMI, and weight) at 90 dayssurrogate

A 90-day structured digital lifestyle intervention with behavioral coaching significantly improves glycemic control and weight in patients with type 2 diabetes, with benefits driven largely by adherence.

Cite This Study

RAYMOND et al. (2026) studied this question.

synapsesocial.com/papers/6a250cbc7def13d035e1cd7dhttps://doi.org/10.2337/db26-1612-p
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 11475-P: Effect of Structured Lifestyle Coaching Outcome on Metabolic Syndrome and Metabolic Age in Type 2 Diabetes: A Three-Month Comparative Study2026
  2. 2Protocol for the Digital, Individualized, and Collaborative Treatment of Type 2 Diabetes in General Practice Based on Decision Aid (DICTA)—A Randomized Controlled Trial2025
  3. 32783-LB: The Diabetes Telemedicine Mediterranean Diet (DiaTeleMed) Study: A Six-Month, Fully Remote, Randomized Clinical Trial Evaluating Personalized Dietary Management in Individuals with Type 2 Diabetes2026
  4. 4Effectiveness of Telemedicine and Electronic Call Reminder and Health Education Trial (TECARE Trial) for Type 2 Diabetes Mellitus: A Randomized Controlled Trial2025
  5. 5A randomised controlled trial of a low-carbohydrate digitally-supported weight loss programme for type 2 diabetes2025