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April 15, 2026Open Access

Ventricular Tachycardia Ablation Outcomes in Patients Without Previous Implantable Cardioverter-Defibrillator Insertion: A Propensity Score-matched Analysis.

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Authors

AAAli Saad Al-ShammariASAnkur SinglaAAA M E E R Awashra

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Overview

Retrospective analysis shows catheter ablation improves in-hospital outcomes for ICD-naive VT patients, suggesting benefits outweigh risks.

Key Points

  • To assess the impact of catheter ablation on in-hospital outcomes in patients with ventricular tachycardia who did not previously have an implantable cardioverter-defibrillator.
  • Conducted a retrospective analysis using the National Inpatient Sample from 2016 to 2021.
  • Identified adult hospitalizations for ventricular tachycardia, excluding those with prior or concurrent ICDs.
  • Utilized multivariable logistic regression and propensity score matching to compare outcomes between ablation and non-ablation groups.
  • Ablation significantly reduced in-hospital mortality (3.17% vs. 8.98%; P < .001).
  • Ablation was associated with lower rates of STEMI (6.82% vs. 18.83%; P < .001) and sepsis (3.38% vs. 10.34%; P < .001).
  • MACEs decreased in the ablation group (15.82% vs. 28.40%; P < .001).
  • Ablation increased rates of cardiac tamponade and cardiogenic shock, indicating potential risks.

Cite This Study

Al-Shammari et al. (2026) studied this question.

synapsesocial.com/papers/69df2a4be4eeef8a2a6af8c5https://doi.org/10.19102/icrm.2026.17033
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Catheter Ablation for Ventricular Tachycardia in Ischemic Cardiomyopathy: A Meta‐Analysis With Reconstructed Time‐to‐Event and Trial Sequential Analysis2025 · 2 citations
  2. 2Ventricular tachycardia ablation in structural heart disease with LV-EF&amp;gt;35%: impact of cardiomyopathy type on outcomes and ICD therapy2026
  3. 3Catheter Ablation for Refractory Ventricular Tachycardia Early After Acute Myocardial Infarction: Management, electrophysiological characteristics and outcomes.2025
  4. 4Ventricular tachycardia ablation in ischaemic cardiomyopathy: who, when and how?2025 · 1 citations
  5. 5A comparative analysis of the safety of ventricular arrhythmia ablation in patients undergoing procedures for ventricular tachycardia and premature ventricular contractions2026