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January 9, 2026NutrientsOpen Access

Low Geriatric Nutritional Risk Index and Mini-Mental State Examination scores were associated with a 116% increased risk of mortality and heart failure readmission in elderly patients.

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Key result

Low Geriatric Nutritional Risk Index and Mini-Mental State Examination scores were associated with a 116% increased risk of mortality and heart failure readmission in elderly patients.

Authors

KNKazutaka NogiTUTomoya UedaAKAtsushi Kyodo

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Overview

Evaluates long-term outcomes in elderly heart failure patients based on nutritional and cognitive assessments, suggesting improved care strategies.

Key Points

  • This research aims to assess how nutritional and cognitive statuses affect long-term outcomes in elderly patients with acute decompensated heart failure.
  • Analyzed data from 414 patients aged ≥65 with acute decompensated heart failure.
  • Categorized patients based on Geriatric Nutritional Risk Index (GNRI) and Mini-Mental State Examination (MMSE) scores.
  • Primary endpoint was composite all-cause mortality and heart failure-related readmission over a median follow-up of 37.4 months.
  • 52.7% of patients reached the composite endpoint of mortality and readmission.
  • Patients with low GNRI and low MMSE had significantly worse outcomes, with an adjusted hazard ratio of 2.16 for the composite outcome.
  • Findings were consistent across different age subgroups.

Cite This Study

Nogi et al. (2026) studied this question. Low Geriatric Nutritional Risk Index and Mini-Mental State Examination scores were associated with a 116% increased risk of mortality and heart failure readmission in elderly patients.

synapsesocial.com/papers/69612fd030ef6c21f6853ca3https://doi.org/10.3390/nu18020189
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Reduced Geriatric Nutritional Risk Index Is Associated with Prevalent Diabetes Mellitus and In-Hospital Mortality in Patients Hospitalized with Heart Failure2026
  2. 2Geriatric nutritional risk index as a predictor of outcomes in elderly patients undergoing percutaneous coronary intervention: An updated systematic review and meta-analysis2025
  3. 3Clinical significance of geriatric nutritional risk index in risk stratification of acute myocarditis2026
  4. 4Association between nutritional status and mortality/neurological outcomes in stroke patients: A systematic review and meta-analysis2025 · 5 citations
  5. 5Prognostic value of the Geriatric Nutritional Risk Index in patients undergoing cardiac surgery: a systematic review and meta-analysis2025 · 10 citations