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January 9, 2026QJM

A diagnostic triad of elevated adenosine deaminase (47 U/L), a positive IGRA, and culture effectively identified tuberculous pericarditis in a resource-limited setting.

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Key result

A diagnostic triad of elevated adenosine deaminase (47 U/L), a positive IGRA, and culture effectively identified tuberculous pericarditis in a resource-limited setting.

Authors

FWFumu WangHWH Wang

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Overview

A case report illustrates a diagnostic triad for tuberculous pericarditis, enabling timely treatment in limited-resource environments.

Key Points

  • To present an effective diagnostic approach for tuberculous pericarditis in resource-limited settings.
  • Case report of a 58-year-old woman with symptoms of fever and dyspnea.
  • Analysis of pericardial fluid for adenosine deaminase and culture.
  • Use of interferon-gamma release assay for diagnosis.
  • Pericardial fluid analysis revealed elevated adenosine deaminase levels (47 U/L).
  • Positive interferon-gamma release assay confirmed tuberculosis infection.
  • Mycobacterium tuberculosis isolated from the fluid culture, leading to appropriate treatment.

Cite This Study

Wang et al. (2026) studied this question. A diagnostic triad of elevated adenosine deaminase (47 U/L), a positive IGRA, and culture effectively identified tuberculous pericarditis in a resource-limited setting.

synapsesocial.com/papers/696128f244c2cd6c68456c3ehttps://doi.org/10.1093/qjmed/hcag007
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diagnostic Challenge of Tuberculous Pleural Effusion: Elevated Adenosine Deaminase (ADA) as the Key Indicator in the Absence of Microbiological Confirmation2025
  2. 2When Tuberculosis Left the Heart in a Cage: Multimodality Imaging Revealing Constrictive Pericarditis in a Young Adult2026
  3. 3Unmasking Tuberculosis: A Case of Pericardial Effusion in a Young Adult With Recurrent Pneumonia2025
  4. 4Navigating Diagnostic Dilemmas in Cardiology: A Rare Case Report of Tuberculosis Presenting as a Cardiac Abscess2025 · 1 citations
  5. 5A case of acute tuberculous pericarditis evolving into pericardial constriction after 32 years: A case report2025