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January 6, 2026Cancer Research CommunicationsOpen Access

Treatment Delays and Survival Divides: Race, Sex, and Early-Onset Colorectal Cancer Disparities

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Authors

TMTsai Meng-HanJCJörge E. CortesMLMinjee Lee

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Overview

Retrospective analysis shows race impacts treatment delays and mortality in early-onset colorectal cancer patients, indicating disparities exist.

Key Points

  • To investigate the impact of sex, race, and treatment timeliness on survival outcomes in early-onset colorectal cancer patients.
  • Conducted a retrospective cohort analysis using SEER data from 2006-2020.
  • Examined associations between sex, race/ethnicity, treatment timeliness, CSS, and OS.
  • Utilized Cox proportional models to analyze survival outcomes.
  • Females had higher treatment timeliness compared to males (73.1% vs. 72.8%).
  • Racial minorities experienced significantly greater delays in treatment.
  • Males and non-Hispanic Black patients showed poorer survival outcomes compared to females and non-Hispanic White patients.

Cite This Study

Meng-Han et al. (2026) studied this question.

synapsesocial.com/papers/695d855e3483e917927a4b76https://doi.org/10.1158/2767-9764.crc-25-0659
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abstract A131: Time tells a different story: Sex and age-related differences in 1-, 3-, and 5-year survival for early-onset CRC in Georgia2025 · 1 citations
  2. 2Racial and ethnic disparities in survival among patients with early-onset primary liver cancer: A 15-year SEER analysis.2026
  3. 3Intersectional analysis of race/ethnicity, geography, and socioeconomic status on colorectal cancer screening utilization and stage at diagnosis: A SEER analysis, 2016-2021.2026
  4. 4Racial and Ethnic Disparities in Survival Among Patients with Cholangiocarcinoma in the United States: A Systematic Review and Meta-Analysis2025 · 2 citations
  5. 5Data from Racial and Ethnic Disparities in Survival among Patients with Cholangiocarcinoma in the United States: A Systematic Review and Meta-analysis2025