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December 23, 2025International Journal of Mathematics and PhysicsOpen Access

CFD Study of the Effect of Coarctation on the Distribution of Velocities, Pressures, and Shear Stresses in the Thoracic Aorta

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Authors

AIAlibek IssakhovUTUliana TimokhinaJNJimin Na

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Overview

Numerical modeling reveals shear stress increases in the thoracic aorta with coarctation, suggesting risks for endothelial dysfunction.

Key Points

  • This research investigates how coarctation affects blood flow dynamics in the thoracic aorta.
  • Numerical modeling using computational fluid dynamics (CFD) methods
  • Analyzed geometric configurations of aorta: normal vs. pathological
  • Utilized Navier-Stokes equations for incompressible non-Newtonian fluid
  • Performed calculations using finite volume method with explicit time-dependent scheme
  • Maximum velocity increased by approximately 1.6 times with coarctation
  • Pressure difference between ascending and descending aorta reached 0.6 kPa
  • Identified localized areas of extreme shear stress potentially leading to endothelial dysfunction

Cite This Study

Issakhov et al. (2025) studied this question.

synapsesocial.com/papers/6949ddb572f746a93d7890f6https://doi.org/10.26577/ijmph.202516210
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