December 8, 2025BloodOpen Access

Household material hardship as a barrier to accessing sickle cell disease curative therapy

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Authors

PMPaul Morgan LDLeanne Duhaney CFCaroline Fry

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Implication

Cross-sectional study finds household material hardship reduces access to curative therapy in children with sickle cell disease, suggesting major socioeconomic barriers.

Key Points

Only 40% of families reported ability to access gene therapy for sickle cell disease due to financial hardship.
Logistic regression showed that household material hardship was associated with 95% lower odds of accessing therapy.
Many children faced multiple domains of vulnerability, including food insecurity and single-parent households.
Study highlights urgent need for interventions targeting socioeconomic barriers to improve access to treatment.

Cite This Study

Morgan et al. (2025) studied this question.

synapsesocial.com/papers/69362f7f4fa91c937236e551 https://doi.org/10.1182/blood-2025-2672

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Implication

Cross-sectional study finds household material hardship reduces access to curative therapy in children with sickle cell disease, suggesting major socioeconomic barriers.

Household material hardship as a barrier to accessing sickle cell disease curative therapy

Discussion

Member takes

Implication

Key Points

Cite This Study

Household material hardship as a barrier to accessing sickle cell disease curative therapy

Discussion

Member takes

Implication

Key Points

Cite This Study

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