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December 8, 2025Blood

National trends in acute lymphocytic leukemia (ALL) incidence (1999–2021): A longitudinal outcome study using joinpoint analysis of age, sex, and regional disparities

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Authors

ACAyesha Cheema

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Overview

Longitudinal analysis shows increased acute lymphocytic leukemia incidence in age groups, highlighting gender, racial, and regional disparities.

Key Points

  • Overall incidence of acute lymphocytic leukemia rose by 34.75% from 1999 to 2021, demonstrating significant trends across demographics.
  • The average annual percent change for women was 1.0002, indicating higher incidence rates compared to men, at 33.196% for men and 36.82% for women.
  • Data analysis incorporated joinpoint regression to assess incidence rates across age groups and identified significant disparities in regional and racial groups.
  • Findings suggest a necessity for targeted interventions to address rising acute lymphocytic leukemia incidence and associated disparities.

Cite This Study

Ayesha Cheema (2025) studied this question.

synapsesocial.com/papers/69362f744fa91c937236e301https://doi.org/10.1182/blood-2025-8040
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