What type of study is this?

This is a Meta-Analysis study (also classified as: Systematic Review).

December 8, 2025BloodOpen Access

Prevalence of iron deficiency with or without anemia in adults: A systematic review and meta-analysis

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Authors

HKHassan KawtharanyPontifícia Universidade Católica do Paraná NMNadine MahmoudBrigham and Women's Hospital AAAbdulkhaliq J. AlsalmanNorthern Border University

Discussion

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Implication

Systematic review reveals 30% prevalence of iron deficiency without anemia in adults, highlighting the need for higher ferritin thresholds for accurate detection.

Key Points

Overall pooled prevalence of iron deficiency across thresholds was 30%.
At a ferritin threshold of <15 mcg/L, the prevalence of iron deficiency was 11%.
Observational analysis assessed 71 studies involving 527,746 adults using serum ferritin cutoffs for prevalence calculation.
Current thresholds for defining iron deficiency may underestimate true prevalence, particularly in premenopausal females.

Cite This Study

Kawtharany et al. (2025) studied this question.

synapsesocial.com/papers/69362f744fa91c937236e2ad https://doi.org/10.1182/blood-2025-6468

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Implication

Systematic review reveals 30% prevalence of iron deficiency without anemia in adults, highlighting the need for higher ferritin thresholds for accurate detection.

Prevalence of iron deficiency with or without anemia in adults: A systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Prevalence of iron deficiency with or without anemia in adults: A systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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