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December 8, 2025BloodOpen Access

Temporal trends in cancer-associated venous thromboembolism mortality: A nationwide analysis (1999–2020)

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Authors

GSGaurav SharmaSPSai Swetha Pavuluri

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Overview

Analysis of national mortality trends reveals increased venous thromboembolism deaths in cancer patients, highlighting gaps in prevention strategies.

Key Points

  • Mortality rates for cancer-associated venous thromboembolism have risen significantly after 2016, indicating a troubling trend.
  • Joinpoint regression identified a 5.33% increase in mortality rates after 2016, following slower rates prior to this point.
  • Data from the CDC WONDER database included individuals aged 15-84 with specified causes of death related to embolism and cancer.
  • The disproportionate impact on black or African American individuals underscores the need for targeted prevention strategies.

Cite This Study

Sharma et al. (2025) studied this question.

synapsesocial.com/papers/69362f6e4fa91c937236e167https://doi.org/10.1182/blood-2025-1352
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