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December 8, 2025BloodOpen Access

Epidemiology and outcomes of patients with myeloproliferative neoplasms in the United States: A SEER database analysis, years 2000-2021

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Authors

SASankalp AroraNSNoha SharafeldinRDRuchi Desai

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Overview

Analysis reveals rising incidence rates and survival differences by sex in patients with myeloproliferative neoplasms, suggesting improved diagnostic approaches.

Key Points

  • The incidence rate of myeloproliferative neoplasms increased, with relative survival of patients showing significant variation.
  • Five-year relative survival rates were 93.3% for Polycythemia Vera, significantly higher than for Primary Myelofibrosis.
  • Demographic data analysis utilized SEER database with retrospective methodology to evaluate patient outcomes across a defined age range.
  • Findings indicate sex-related differences in survival, confirming previous smaller studies' results but on a larger scale.

Cite This Study

Arora et al. (2025) studied this question.

synapsesocial.com/papers/69362f4b4fa91c937236d77chttps://doi.org/10.1182/blood-2025-2048
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinicopathological characteristics and outcome of patients with Philadelphia negative myeloproliferative neoplasms: first report from Upper Egypt2025
  2. 2Myeloproliferative neoplasms in Mexico: An analysis of clinical features, driver mutations, and disease progression patterns in a case series.2025
  3. 3Myeloproliferative neoplasms-unclassifiable (MPN-U): A carefully curated series of 30 Mayo Clinic patients2025
  4. 4Treatment landscape and outcome of myeloproliferative neoplasms in asia: Interim analysis of the Asian myeloproliferative neoplasm registry2025
  5. 5Sex-based disparities in MPN treatment patterns: A study of 1167 patients from the Quebec MPN registry2025