What type of study is this?

This is a Human Clinical Trial study.

December 8, 2025BloodOpen Access

Outcomes of low-intensity AML therapy based on treatment facility

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Authors

ALAustin LarsonChildren's Hospital Colorado SCSanyogita ChandraBharat Immunologicals and Biologicals Corporation (India)

Discussion

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Implication

Retrospective analysis shows similar overall survival in acute myeloid leukemia patients treated at academic and community centers, indicating varied treatment patterns.

Key Points

Overall survival was comparable between academic and collaborative/community centers, despite different treatment patterns.
Patients with TP53 mutations had worse overall survival, highlighting the importance of molecular factors in treatment.
Multivariable analysis utilized logistic regression and identified significant predictors of survival and treatment response.
Significant differences were observed in usage of specific agents like azacitidine and venetoclax across treatment settings.

Cite This Study

Larson et al. (2025) studied this question.

synapsesocial.com/papers/69362f3a4fa91c937236d3c9 https://doi.org/10.1182/blood-2025-4629

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Implication

Retrospective analysis shows similar overall survival in acute myeloid leukemia patients treated at academic and community centers, indicating varied treatment patterns.

Outcomes of low-intensity AML therapy based on treatment facility

Discussion

Member takes

Implication

Key Points

Cite This Study

Outcomes of low-intensity AML therapy based on treatment facility

Discussion

Member takes

Implication

Key Points

Cite This Study

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Also Consider