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December 8, 2025BloodOpen Access

Early-stage nodular lymphocyte predominant Hodgkin lymphoma: Disease characteristics, treatment pattern, and long-term outcomes from a tertiary care cancer institute in India

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Authors

JGJayant Sastri GodaAKAnkita KanojaASAlok Shetty

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Overview

Observational study shows favorable long-term outcomes in early-stage Hodgkin lymphoma, indicating treatment patterns impact survival rates.

Key Points

  • To report the clinical characteristics, treatment patterns, and long-term outcomes of early-stage NLPHL patients.
  • Included consecutive patients diagnosed with Stage I–II NLPHL from 2010 to 2022.
  • Categorized treatment modalities into radiotherapy, chemotherapy, combined modality, and observation.
  • Estimated survival outcomes using the Kaplan–Meier method.
  • Median age of patients was 31 years, with a male predominance of 75%.
  • Treatment included radiotherapy (51%) and combined modality treatment (43%), with decent progression-free survival of 91%.
  • Overall survival at 8 years was 98%, demonstrating low rates of lymphoma-related deaths.

Cite This Study

Goda et al. (2025) studied this question.

synapsesocial.com/papers/69362f364fa91c937236d2e1https://doi.org/10.1182/blood-2025-5404
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Real world outcome of nodal T cell non-Hodgkin lymphoma from hematology cancer consortium registry in India2025
  2. 2Real world epidemiological trends in nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), England 2014-2021: Preliminary data from the uncover Study group2025
  3. 3Outcomes of allogeneic hematopoietic stem cell transplantation in nodular lymphocyte-predominant Hodgkin lymphoma: A registry-based study from the EBMT-LWP2025
  4. 4Academic cancer programs deliver improved long-term survival in nodular lymphocyte predominant Hodgkin lymphoma: Insights from 7,000+ United States patients2025
  5. 5Treatment practices and outcomes of advanced stage classical Hodgkin lymphoma in India: An analysis from the hematology cancer consortium2025