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December 8, 2025BloodOpen Access

Determinants of survival in primary cutaneous anaplastic large cell lymphoma (pcALCL): Analysis of a real-world pooled database

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Authors

AGAnkita GuptaUniversity of Louisville

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Implication

Analysis finds prognostic factors impact survival and recurrence in T-cell lymphoma, highlighting therapy options.

Key Points

  • This analysis aims to identify survival determinants in primary cutaneous anaplastic large cell lymphoma (pcALCL).
  • Compiled a pooled database of real-world cases diagnosed with pcALCL.
  • Utilized Kaplan-Meier survival curves and Cox proportional hazards model for analysis.
  • Excluded cases of pcALCL coexisting with LYP or MF.
  • Median overall survival was 156 months with influential factors identified.
  • Prognostic factors included recurrence, immunosuppression, and therapeutic interventions.
  • Survival improved with treatment modalities compared to no treatment.

Cite This Study

Ankita Gupta (2025) studied this question.

synapsesocial.com/papers/69362f364fa91c937236d2dehttps://doi.org/10.1182/blood-2025-5411
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Outcomes of primary cutaneous anaplastic large cell lymphoma across u.S. cancer care settings: A national cancer database analysis.2025
  2. 2Primary Cutaneous Anaplastic Large Cell Lymphoma with Locoregional Lymph Node Involvement: Challenges in Diagnosis and Clinical Management2025
  3. 3Clinical features and prognostic outcomes of systemic anaplastic large cell lymphoma in a Chinese multicenter study2025
  4. 4Primary Cutaneous Follicle Center Lymphoma2025 · 1 citations
  5. 5Identifying biological differences between two clinical risk groups of cutaneous CD30+ T cell lymphoproliferative disorders2025