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December 8, 2025BloodOpen Access

Outcomes of primary cutaneous anaplastic large cell lymphoma across u.S. cancer care settings: A national cancer database analysis.

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Authors

EKErin KaserSKSupreet Kaur

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Overview

Retrospective analysis shows equivalent outcomes for primary cutaneous anaplastic large cell lymphoma in academic and community cancer programs, suggesting comparable care.

Key Points

  • This study aims to analyze demographics, treatment patterns, and outcomes of primary cutaneous anaplastic large cell lymphoma (PC-ALCL) across different U.S. cancer care settings.
  • Conducted a retrospective analysis of PC-ALCL cases reported to the National Cancer Database between 2004 and 2022.
  • Compared demographic, clinical, and survival data between patients treated at academic cancer programs (ACPs) and community cancer programs (CCPs).
  • Utilized Kaplan-Meier and Cox proportional hazards models to compare overall survival (OS) based on various factors.
  • 2,618 PC-ALCL patients identified, with similar male to female ratios across ACPs and CCPs.
  • CCP-treated patients were older, median age 69 vs. 65 years for ACPs.
  • No statistically significant survival advantage for treatment at ACPs compared to CCPs, suggesting equivalent care.

Cite This Study

Kaser et al. (2025) studied this question.

synapsesocial.com/papers/69362f364fa91c937236d2dfhttps://doi.org/10.1182/blood-2025-5419
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