What question did this study set out to answer?

To evaluate the clinical outcomes of mycosis fungoides and sézary syndrome patients treated at academic versus community cancer programs.

December 8, 2025BloodOpen Access

Comparative outcomes of 14,650 patients with mycosis fungoides/Sézary syndrome from academic and community cancer programs

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To evaluate the clinical outcomes of mycosis fungoides and sézary syndrome patients treated at academic versus community cancer programs.
Retrospective review of 14,650 cases from National Cancer Data Base (2004-2022)
Comparison of demographics, clinical, and survival data between patients treated at academic and community programs
Used Kaplan-Meier and Cox proportional hazards models to assess overall survival.
Patients at academic cancer programs had higher overall survival rates (14 years vs 11 years, p < 0.001)
The 2-year survival rate was 88.7% at academic centers compared to 82.2% at community centers
Patients at academic centers were younger at diagnosis and received treatment faster compared to those at community centers.

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Retrospective analysis shows better survival for mycosis fungoides/sézary syndrome in academic over community cancer programs.

Velázquez et al. (2025) studied this question.

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