Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025BloodOpen Access

Unequal outcomes: The role of institutional setting in the management of primary CNS lymphoma

View Full Paper
Ask AI
Bookmark
Share

Authors

LBLeyla BojaniniThe University of Texas Health Science Center at San AntonioEAEleftheria AtallaThe University of Texas Health Science Center at San AntonioADAdolfo Diaz DuqueTexas A&M University – San Antonio

Discussion

Loading...

Member takes

Overview

Retrospective cohort study reveals disparities in survival and treatment protocols for PCNSL across facility types, indicating higher mortality in socioeconomically disadvantaged patients.

Key Points

  • To evaluate how treatment facility type and sociodemographic factors influence treatment patterns and survival in PCNSL.
  • Retrospective cohort study using National Cancer Database data from 2004 to 2022
  • Comparison of treatment facility types: Academic Cancer Programs vs Community Cancer Programs
  • Statistical analyses including Kaplan-Meier and Cox proportional hazards models
  • 65% of patients were treated at Academic Cancer Programs, with longer median survival of 19.6 months
  • Patients at Community Cancer Programs had higher mortality rates and treatment delays
  • Significant differences in treatment rates and survival across facility types, even after adjusting for comorbidity indices.

Cite This Study

Bojanini et al. (2025) studied this question.

synapsesocial.com/papers/693624ce4fa91c937236cf95https://doi.org/10.1182/blood-2025-4493
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Real-world treatment patterns and survival outcomes in primary CNS lymphoma: Analysis of the national cancer database2025 · 1 citations
  2. 2Facility-level disparities in outcomes of subcutaneous panniculitis-like T-cell lymphoma: A national cancer database analysis2025
  3. 3Patients with burkitt's lymphoma have a better survival probability if treated in an academic cancer program2025
  4. 4Academic cancer programs deliver improved long-term survival in nodular lymphocyte predominant Hodgkin lymphoma: Insights from 7,000+ United States patients2025
  5. 5The academic center effect: Better outcomes for patients with DLBCL2025