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December 5, 2025European journal of medical researchOpen Access

Research progress on m6A RNA methylation modification in human reproduction related diseases

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Authors

XSXuesong SuiYLYulu LiuZWZiqing Wang

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Overview

This review highlights therapeutic strategies and prevention methods for reproductive disorders influenced by m6A in human reproduction.

Key Points

  • m6A RNA methylation plays a critical role in regulating fertility-related processes and disorders.
  • Emerging evidence shows that m6A is involved in conditions like asthenozoospermia and polycystic ovary syndrome.
  • This review explores the molecular pathways of m6A RNA methylation and its impacts on reproduction.
  • Understanding these mechanisms may lead to innovative strategies for diagnosis and prevention of reproductive health issues.

Cite This Study

Sui et al. (2025) studied this question.

synapsesocial.com/papers/693231118e51979591dce06chttps://doi.org/10.1186/s40001-025-03481-8
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1N6-Methyladenosine RNA Methylation: A Key Regulator in Male Reproductive Disorders and Urological Cancers2025 · 2 citations
  2. 2m6A Methylation Modification: Perspectives on the Early Reproduction of Females2025
  3. 3RNA Modifications in Health and Disease2025
  4. 4m6A RNA Methylation in Psychiatric Disorders: An Emerging Epitranscriptomic Axis2025
  5. 5m6A modification of non‑coding RNA: Mechanisms, functions and potential values in human diseases (Review)2025 · 12 citations