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December 4, 2025Saudi Pharmaceutical JournalOpen Access

Relevance of topical application of minoxidil laden nano-lipid for hair growth enhancement

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Authors

AAAli M. AlghazalBABandar AlduhbiabHEHeba S. Elsewedy

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Overview

This research demonstrates enhanced hair growth from a minoxidil nanoemulsion in mice, suggesting transdermal delivery could address hypertrichosis.

Key Points

  • The optimized nanoemulsion achieved a 75.6% in vitro release over 6 hours and improved hair growth rates over 28 days.
  • Developed using Response Surface Methodology, the formulation's viscosity was 26.7 cP and particle size was 83.1 nm.
  • In vivo testing confirmed the stability and effectiveness of the minoxidil nanocarrier for hair loss treatment.
  • Findings highlight the potential of nanoemulsions in enhancing topical drug delivery for addressing hypertrichosis.

Cite This Study

Alghazal et al. (2025) studied this question.

synapsesocial.com/papers/6930e8b6ea1aef094cca2e91https://doi.org/10.1007/s44446-025-00051-1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Nitric Oxide Donor and Minoxidil Co‐Loaded Microneedles Improving Hair Loss Treatment2025
  2. 2Natural Sweetener Stevioside‐Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia2025
  3. 3Enhancing targeted delivery and efficacy of PEGylated liposomal doxorubicin with liposomal minoxidil: comprehensive in silico, in vitro, and in vivo tumor model studies2025 · 1 citations
  4. 4A Review On Minoxidil a Potent Hair growth Agent2025
  5. 5Formulation Development and In-Vitro Evaluation of Glycerosomes Containing Mionoxidil for Topical Application2025