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December 4, 2025Netherlands Heart JournalOpen Access

The impact of aging on acute coronary syndromes: an EHR-based analysis

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Authors

CSCharlotte E. P. SiegersJRJan van Ramshorst

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Overview

Analysis shows invasive strategy improves outcomes in older adults with acute coronary syndrome, indicating tailored approaches may benefit age groups.

Key Points

  • Invasive strategy led to improved outcomes in all-cause mortality for nonagenarians with acute coronary syndrome.
  • Patients aged 85–89 experienced significantly lower mortality rates at 30 days compared to younger groups, indicating age-related outcomes.
  • Consecutive cohort study analyzed 1,036 octo and nonagenarians among 6,168 acute coronary syndrome patients across three age groups.
  • Identifying age groups and outcomes highlights potential for safer invasive strategies in older adults.

Cite This Study

Siegers et al. (2025) studied this question.

synapsesocial.com/papers/6930dc9eea1aef094cca2cd7https://doi.org/10.1007/s12471-025-02003-9
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acute Coronary Syndrome Management in Older Patients: A Dual-Center Retrospective Cohort Study2025
  2. 2Clinical Outcomes After Immediate Coronary Angiography in Elderly Versus Younger Patients Suffering from Acute Coronary Syndrome2025
  3. 3Clinical presentation and outcomes of acute myocardial infarction with vs. without st elevation in octogenarians2025 · 1 citations
  4. 4Nationwide Trends in PCI Outcomes for Older Acute Coronary Syndrome Patients with a History of CABG2026
  5. 5A personalized approach to determining the indications and strategy for coronary artery bypass grafting in elderly and geriatric patients2025