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April 13, 2026Current Cardiology Reviews

Between 2016 and 2020, post-catheterization bleeding declined (1.5% vs 0.7%, P<0.001) and Impella use increased (1.2% vs 2.1%, P<0.001), with no significant difference in all-cause mortality.

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Why the study?

Does percutaneous coronary intervention (PCI) over time (2016-2020) improve clinical outcomes in older ACS patients with a history of CABG?

Population

94,610 ACS patients aged 65 and older with a history of CABG undergoing PCI, median age 75, 74.5% male.

Comparison

Percutaneous coronary intervention between 2016… vs Temporal comparison (2016 vs. 2020)

Design

Cohort

Authors

SSSidhartha Gautam SenapatiTMTanisha MishraAGAnupama Gupta

Discussion

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Overview

In older ACS patients with prior CABG undergoing PCI, bleeding complications have decreased and Impella use has increased from 2016 to 2020, though mortality remains unchanged.

Key Points

  • This research aims to assess current trends in PCI outcomes among older ACS patients with a CABG history.
  • Analyzed data from the 2016-2020 National Inpatient Sample database
  • Focused on PCI outcomes for patients aged 65 and older with prior CABG
  • Measured outcomes included post-catheterization bleeding and respiratory failure
  • 94.6% of patients underwent non-elective PCI
  • Declining trends in post-catheterization bleeding from 1.5% in 2016 to 0.7% in 2020
  • Increased Impella usage from 1.2% in 2016 to 2.1% in 2020
  • No significant differences observed in all-cause mortality or other major complications

Structured PICO

Does percutaneous coronary intervention (PCI) over time (2016-2020) improve clinical outcomes in older ACS patients with a history of CABG?

P
Population
94,610 ACS patients aged 65 and older with a history of CABG undergoing PCI, median age 75, 74.5% male.
I
Intervention
Percutaneous coronary intervention (PCI) between 2016 and 2020
C
Comparator
Temporal comparison (2016 vs. 2020)
O
Outcome
Trends in PCI outcomes including post-catheterization bleeding, post-procedural respiratory failure, and Impella usagehard clinical

In older ACS patients with prior CABG undergoing PCI, bleeding complications have decreased and Impella use has increased from 2016 to 2020, though mortality remains unchanged.

Cite This Study

Senapati et al. (2026) studied this question.

synapsesocial.com/papers/69dc88d83afacbeac03ea97bhttps://doi.org/10.2174/011573403x417319251222084028
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