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December 4, 2025Pharmacognosy MagazineOpen Access

Narirutin Induces Cytotoxicity and Apoptosis in Gastric Cancer Cells Through Oxidative Stress Modulation

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Authors

ZPZhong-Ting PanYGYanling GuoZPZhong-Ting Pan

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Overview

Experimental analysis shows narirutin enhances apoptosis in gastric cancer cells, suggesting potential therapeutic application.

Key Points

  • Narirutin treatment significantly increased apoptotic markers in human gastric adenocarcinoma cells, indicating effective cytotoxicity.
  • The study demonstrated that oxidative stress levels rose proportionally with narirutin dosage, suggesting a pro-oxidant mechanism.
  • Assessment utilized MTT assays and acridine orange/ethidium bromide staining to evaluate cell viability and apoptosis.
  • These results provide insights into narirutin's mechanisms, highlighting its potential role in gastric cancer therapies.

Cite This Study

Pan et al. (2025) studied this question.

synapsesocial.com/papers/6930dc92ea1aef094cca2a6dhttps://doi.org/10.1177/09731296251391926
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