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December 4, 2025Journal of Proteome ResearchOpen Access

Exploring Biomarkers in Type 2 Diabetes Mellitus versus Normoglycemia Identified through High-Throughput Proteomics: A Systematic Review and Meta-Analysis

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Authors

GTGuillermo L. Taboada

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Overview

Systematic review synthesizes evidence from proteomic profiles in type 2 diabetes, suggesting promising biomarkers for metabolic regulation.

Key Points

  • Proteomic analysis identified multiple biomarkers for type 2 diabetes, with implications for better understanding metabolic disturbances.
  • A systematic review across 27 studies highlighted key proteins involved in immune response, lipid metabolism, and glucose regulation.
  • Meta-analysis pointed to consistent biomarkers among studies, showcasing the utility of proteomics in diabetes research.
  • An interactive tool, metaMarkersT2D, was developed to enhance data accessibility and facilitate further research efforts.

Cite This Study

Guillermo L. Taboada (2025) studied this question.

synapsesocial.com/papers/6930dc6bea1aef094cca1f28https://doi.org/10.1021/acs.jproteome.5c00773
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