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December 2, 2025Journal of Clinical ImmunologyOpen Access

Exosomes in Autoimmunity: Mediators of Autoantigen Presentation and Targets for Therapeutic Intervention in Autoimmune Diseases

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Authors

HAHailah M. AlmohaimeedSSSurbhi Singh

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Overview

Review highlights exosomes' role in autoantigen presentation and immune dysregulation in autoimmune diseases, suggesting new therapeutic interventions.

Key Points

  • Exosomes positively impact immune dysregulation in autoimmune diseases, highlighting their therapeutic potential.
  • Key findings indicate that exosomes influence self-tolerance, leading to persistent autoimmune responses.
  • Assessment focused on exosomal mechanisms involved in immune tolerance breakdown, linking to intervention strategies.
  • Prioritizing exosomal pathways may enable more precise treatments for patients with autoimmune disorders.

Cite This Study

Almohaimeed et al. (2025) studied this question.

synapsesocial.com/papers/692e3da16c9b3ab28c187bdchttps://doi.org/10.1007/s10875-025-01965-0
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