November 30, 2025Nature CommunicationsOpen Access

Factorized embedding of goal and uncertainty in the lateral prefrontal cortex guides stably flexible learning

View Full Paper

Ask AI

Bookmark

Goal pursuit is influenced by uncertainty, showing the importance of resilience in decision-making.
Model-based learning improves performance under uncertainty, unlike model-free learning which can struggle.
fMRI data indicates activity in the lateral prefrontal and orbitofrontal cortex during the goal-directed task.
Resilience to uncertainty correlates with participants' ability to maintain flexible goal-directed behavior.

Discussion

No takes yet. Share an insight, caveat, or question.

Model simulations reveal flexible goal pursuit in uncertain environments, suggesting resilience in the lateral prefrontal cortex plays a key role.

Sung et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Model simulations reveal flexible goal pursuit in uncertain environments, suggesting resilience in the lateral prefrontal cortex plays a key role.